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During the current analyze we explain AZ191, a strong modest molecule inhibitor that selectively inhibits DYRK1B in vitroThe latter outcome is mediated from the hitherto unidentified ability of DYRK1B to activate the PI3K/mTOR/AKT pathway, which is known to stabilize GLI proteins [seven, 26]. The PI3K/mTOR/AKT pathway is Among the most routinely a

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